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KMID : 0355420200440040175
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Journal of Korean Academy of Oral Health
2020 Volume.44 No. 4 p.175 ~ p.179
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Inhibitory effect of mastic oil on Streptococcus mutans growth
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Lee Doh-Hyun
Kim Ji-Hye
Im Sagn-Uk
Jung Yun-Sook
Choi Youn-Hee
Song Keun-Bae
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Abstract
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Objectives: The aim of this study was to examine the antibacterial effect of mastic oil on a representative caries-inducing bacterium, Streptococcus mutans.
Methods: S. mutans UA159 was maintained in a BHI medium containing 0.1% sugar at 37℃ and 10% CO2. Strains were treated with six different concentrations of mastic oil (0, 0.1, 0.2, 0.3, 0.4, 0.5%). After incubation for 16 h, the antibacterial effect was evaluated by measuring the optical density (OD) and observing the colony-forming unit. A microtiter plate assay was performed to analyze the anti-adhesion ability of mastic oil on S. mutans.
Results: More than 0.1% of mastic oil inhibited the growth of S. mutans. In addition, 0.4% mastic oil exterminated S. mutans. Mastic oil induced an anti-adhesive ability in S. mutans.
Conclusions: These results suggest that mastic oil may be used as a preventive measure against dental caries.
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KEYWORD
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Antibacterial effect, Mastic oil, Streptococcus mutans
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